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Zebrafish is a vertebrate so it has a body plan fundamentally similar to ours onai et al 2014 like humans zebrafish have a notochord that is a central pile of turgescent cells that confers rigidity to embryo and larvae and serves as the support axis for the development of the spinemuscles are located on both sides of the notochordneuroscience research using non human primate models and genome editing 75 enabled us to generate genome assemblies and gene coding sequence analysis more efciently and provided a basis for pdf | the use of aquatic model organisms has been greatly diversified in laboratories zebrafish is the most advanced aquatic species for the use of crispr cas9 in laboratories because of the r jaenisch et al eds genome editing in neurosciences research and perspectives in neurosciences doi 101007978 3 319 60192 2 1 1 detailed knowledge of disease causing mutations and genes allows the establish ment of reliable and disease relevant cellular and animal models and facilitates thesharif tabebordbar is a postdoctoral fellow in the sabeti lab sharifs research is focused on engineering adeno associated viruses aavs to develop tissue specific gene delivery vehicles and to improve safety of aav mediated gene delivery for gene editing applications

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